Cortisol, Six Specimens
Use
The Cortisol, Six Specimens test is used to assess adrenal gland function by measuring cortisol levels in the serum. This sequential sampling over the course of the day helps in diagnosing conditions related to abnormally high or low cortisol levels, such as Addison's disease or Cushing's syndrome. It provides a detailed diurnal curve, which is essential for understanding the body's cortisol secretion pattern.
Special Instructions
Not provided.
Limitations
The test may exhibit interference due to biotin consumption, which can cause inaccurate results. It is essential to ensure the patient has discontinued biotin supplements at least three days prior to sample collection. The volume required (minimum of 0.7 mL) does not allow for repeat testing, thus proper collection and handling are crucial.
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
Cortisol
Analyte
LOINC Codes
- 43215-3 - Cortis BS SerPl-mCnc
- 21223-3 - Cortis sp1 p chal SerPl-mCnc
- 12557-5 - Cortis sp2 p chal SerPl-mCnc
- 12558-3 - Cortis sp3 p chal SerPl-mCnc
- 12559-1 - Cortis sp4 p chal SerPl-mCnc
- 12560-9 - Cortis sp5 p chal SerPl-mCnc
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.7 mL
Container
Gel-barrier tube (preferred) or red-top tube
Collection Instructions
If a red-top tube is used, transfer separated serum to a plastic transport tube.
Patient Preparation
Patients should stop biotin consumption at least 72 hours prior to the collection of a sample.
Storage Instructions
Room temperature
Other tests from different labs that may be relevant