Dehydroepiandrosterone (DHEA) Sulfate, Two Specimens
Use
Dehydroepiandrosterone (DHEA) sulfate is an important indicator of adrenal gland function and is useful in the diagnosis of adrenal disorders. This test is used to measure the level of DHEA sulfate in the blood, which can help assess adrenal function, diagnose adrenal tumors or hyperplasia, and evaluate hirsutism or virilism in women. It is also used in the assessment of precocious puberty in children and can aid in the investigation of anovulation in women.
Special Instructions
This panel requires multiple specimens to be collected at different times. An initial baseline sample is collected, followed by additional samples after administering a treatment such as a drug or glucola. It's crucial to consult with a clinician before collecting this series to confirm the necessity of the series panel. Patients taking high doses of biotin should refrain from supplementation at least 72 hours before sample collection to avoid interference.
Limitations
This test may show interference if the patient's blood sample is collected while they are taking high doses of biotin (vitamin B7/B8). The assay's performance might be affected in such cases, necessitating a need to temporarily stop biotin intake as recommended prior to testing. Additional factors such as the timing of sample collection and proper adherence to collection protocol might also impact the test results.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 56552-3
- 46963-5
- 16723-9
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Collect blood samples at specified time points as detailed in the collection protocol, ideally post-treatment administration.
Patient Preparation
Patients should stop biotin consumption at least 72 hours prior to sample collection to prevent interference.