Fluorescence in situ Hybridization (FISH), Oncology
Use
Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability).
Special Instructions
Not provided.
Limitations
The test will not detect molecular mutations or chromosomal alterations not targeted by the probe included in the profile. Testing is performed once the needed probes and diagnosis are received. The FDA has determined that clearance or approval is not necessary for this test, and it should not be regarded as investigational or for research purposes.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 31208-2 - Specimen source
- 62361-1 - Cells counted
- 62360-3 - Cells analyzed
- 62356-1 - Chrom analy result (ISCN)
- 62365-2 - Diagnostic imp Spec-Imp
- 48672-0 - Clinical cytogeneticist Spec
- 11502-2 - Laboratory report
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL (adult), 5 mL (pediatric)
Minimum Volume
5 mL (adult), 1 mL (pediatric)
Container
Green-top (sodium heparin) tube; pediatric Vacutainer is optimal or lavender-top (EDTA) tube (suboptimal)
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Broken or dirty slides; excessive cellular debris or stained slides; frozen specimen
Other tests from different labs that may be relevant