Follicle-stimulating Hormone (FSH) and Luteinizing Hormone (LH)
Also known as: FSH and LH, LH and FSH, Luteinizing Hormone (LH) and Follicle-stimulating Hormone (FSH)
Use
Follicle-stimulating Hormone (FSH) and Luteinizing Hormone (LH) testing is crucial for evaluating reproductive functions in individuals. These hormones play vital roles in the regulation of the menstrual cycle and stimulation of ovarian follicles in women. In men, they are important for testes function and sperm production. This test is often ordered when investigating conditions such as hypogonadism, infertility, and menstrual irregularities. It can also aid in diagnosing pituitary or hypothalamic disorders.
Special Instructions
This test may exhibit interference when samples are collected from individuals consuming a supplement with a high dose of biotin (also known as vitamin B7, vitamin H, or coenzyme R). It is recommended to inquire about biotin supplementation for all patients indicated for this test. Patients should stop consuming biotin at least 72 hours prior to sample collection to avoid interferences in test results.
Limitations
The assay may have limited capability if the sample is affected by high-dose biotin supplementation. Additionally, results can be influenced by the presence of heterophile antibodies, rheumatoid factor, or other substances in the blood that may interact with the assay components. The test's accuracy and performance can vary based on sample handling, storage conditions, and the precise methodology used across different laboratories.
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 34549-6
- 10501-5
- 15067-2
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1.5 mL
Minimum Volume
0.7 mL
Container
Red-top tube, gel-barrier tube
Collection Instructions
If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.
Patient Preparation
Patients should stop biotin consumption at least 72 hours prior to sample collection.
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |