HBV Baseline Evaluation, HCV Direct-acting Antivirals
Also known as: Hepatitis
Use
Risk assessment and management of HBV infection status in patients prior to initiation of HCV treatment with direct-acting antiviral agents.
Special Instructions
Not provided.
Limitations
The HBV quantitative real-time PCR assay used in this evaluation has a quantitative detection range of 10 to 1,000,000,000 IU/mL. This limitation may affect the precise quantification at very low or high levels beyond the specified range. Additionally, biotin interference is a potential limitation if patients do not follow the specified guidelines to avoid biotin supplementation before test collection.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 77190-7 - HBV core + surf Ab + surf Ag Pnl Ser
- 5196-1 - HBV surface Ag SerPl Ql IA
- 22322-2 - HBV surface Ab Ser Ql
- 13952-7 - HBV core Ab SerPl Ql IA
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
7.5 mL
Minimum Volume
2.9 mL
Container
Gel-barrier tube or red-top tube
Collection Instructions
Two samples must be submitted. If tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube. Centrifuge sample within 24 hours of collection. Transfer serum/plasma to a screw-cap polypropylene transport tube. Ship frozen (preferred).
Patient Preparation
Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.
Storage Instructions
Room temperature (preferred) up to 14 days. Refrigerated up to 14 days. Frozen up to 14 days. For HBV DNA: Frozen (preferred) up to 12 weeks. Refrigerated up to 6 days. Room temperature up to 24 hours.
Causes for Rejection
Heat-inactivated specimens; cord blood; cadaveric specimens; or body fluid other than serum or EDTA plasma; gross hemolysis; excessive lipemia; improper labeling
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant