High-density Lipoprotein Cholesterol (HDL-C)

Casandra

Casandra Test Code LC82995Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 001925CPT Code 83718

High-density Lipoprotein Cholesterol (HDL-C)

Also known as: Alpha-Lipoprotein Cholesterol, HDL Cholesterol, HDL Cholesterol Electrophoresis, HDLC

Clinical Use

Order Test

Use

Monitoring of HDL-cholesterol in serum is of clinical importance since an inverse correlation exists between serum HDL-cholesterol concentrations and the risk of atherosclerotic disease. Elevated HDL-cholesterol concentrations are protective against coronary heart disease, while reduced HDL-cholesterol concentrations, particularly in conjunction with elevated triglycerides, increase the cardiovascular risk.2,3 Strategies have emerged for treating cardiovascular disease by increasing HDL-cholesterol levels.4,5

Special Instructions

Not provided.

Limitations

Decreased HDL-C can be due to genetic factors like primary hypoalphalipoproteinemia, lifestyle factors such as cigarette smoking, obesity, hypertriglyceridemia, and lack of exercise, or medications such as steroids, thiazides, beta-adrenergic blockers, probucol, and neomycin. HDL-C is especially low in obese, sedentary men, smokers, and those with diabetes mellitus. Uremia is also associated with lower HDL-C levels.

Test Details

Methodology

Automated Analyzer (Clinical Chemistry)

Biomarkers

LOINC Codes

Order Codes

2085-9 - HDLc SerPl-mCnc

Result Codes

2085-9 - HDLc SerPl-mCnc

Result Turnaround Time

1 day

Specimen

Serum

Volume

1 mL

Minimum Volume

0.7 mL

Container

Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube. Do not use oxalate, EDTA, or citrate plasma.

Collection Instructions

Separate serum or plasma from cells within 45 minutes of collection.

Patient Preparation

Patient should be on a normal diet and maintain a stable weight for a week prior to testing. Any drugs should be discontinued for three to four weeks if possible. Fasting is not necessary.