HLA B*15:02, Carbamazepine Sensitivity

Casandra

Casandra Test Code LC67342Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 167129CPT Code 81381

HLA B*15:02, Carbamazepine Sensitivity

Also known as: B1502, Carbamazepine Sensitivity, HLA B*1502, HLA B1502

Clinical Use

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Use

This test has been recommended for patients of Asian descent who are being considered for carbamazepine therapy. The utility of this test for patients of other ethnic backgrounds has not been established.

Special Instructions

Contact HLA customer service at 800-533-1037 for assistance in selecting the appropriate HLA test for the patient. Use a buccal swab kit provided by LabCorp for buccal specimens. For more information about specimen collection and shipment, also reach out to customer service.

Limitations

Even with strict collection and testing protocols, there is a chance that an occasional specimen may be unsuitable for testing. In those instances, an additional sample might be needed. It's important to note that the absence of the HLA B*15:02 allele does not entirely eliminate the risk of an adverse drug reaction. The test has not been cleared or approved by the FDA, and its utility outside of the Asian population has not been conclusively established.

Test Details