Human T-Cell Lymphotropic Virus 1, 2 (HTLV-1/HTLV-2) Antibodies, Preliminary Test With Confirmation
Also known as: HTLV-I/HTLV-II
Use
Screen patients for infection with human T-lymphotropic virus and, if positive, confirm infection with either HTLV-1 or HTLV-2
Special Instructions
This test involves a preliminary chemiluminescent microparticle immunoassay (CMIA) and, if positive, a confirmation by line blot (immunoblot) to delineate between HTLV-1 and HTLV-2 infection. Coordination with the ordering provider is necessary to schedule specimen pick-up.
Limitations
HTLV-1 or HTLV-2 immunoblot testing should only be performed on patient specimens previously found positive for HTLV infection by immunoassay (EIA). False results can occur based on assay sensitivity and specificity. Confirmatory testing is part of the procedure to help reduce false positives and determine specific virus presence, but limitations inherent in the testing methodology and specimen quality can affect accuracy.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 29901-6
- 29901-6
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1.5 mL
Container
Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube
Collection Instructions
Centrifuge sample to separate serum or plasma. For non-gel-barrier tubes, transfer serum or plasma to a plastic transport tube.
Storage Instructions
Refrigerate.
Causes for Rejection
Gross bacterial contamination; hemolysis; lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 6 months |