Lipid Panel With Diabetes Risk Index (DRI)
Use
The Diabetes Risk Index (DRI) is intended for use in adult subjects for the quantitative determination of a risk score in serum or plasma. The DRI score (1-100) may be used as an aid in stratifying the risk of developing type 2 diabetes in individuals with normo-glycemia or prediabetes. The Diabetes Risk Index (DRI) is a nuclear magnetic resonance spectroscopy (NMR)-derived multimarker score (values 1-100) that predicts a patient's risk of developing type 2 diabetes mellitus (T2D) independent of glycemic status. DRI derives its performance from the weighted addition of the Lipoprotein Insulin Resistance Index (LP-IR) scores with simultaneously-measured levels of branched-chain amino acids (BCAA).1-6
Special Instructions
Patient fasting is not required; however, fasting for 12 to 14 hours prior to blood draw is recommended in scenarios where triglyceride values offer diagnostic information for conditions like familial hypercholesterolemia, early onset heart disease, or pancreatitis.
Limitations
LDL cholesterol will not be calculated if triglyceride levels are above 800 mg/dL. DRI measurements from plasma specimens are typically 8 points lower than those obtained from serum specimens. This test has not been cleared or approved by the FDA.
Methodology
Other
Biomarkers
LOINC Codes
- 2093-3
- 2571-8
- 2085-9
- 43396-1
- 13457-7
- 94560-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plain red-top tube (preferred); NMR LipoTube (black-and-yellow-top tube)
Collection Instructions
Collect specimen in a plain red-top tube (no gel), hold upright at room temperature for 45 minutes to clot, then centrifuge. Transfer to a transport tube for storage at 2°C to 8°C until shipment.
Patient Preparation
Patient fasting is not required but recommended for certain conditions.
Storage Instructions
Refrigerate.
Causes for Rejection
Unspun LipoTube or unseparated plain red-top or EDTA tube; serum or plasma specimen drawn in a gel-barrier collection tube other than the NMR LipoTube.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | LipoTube Serum: 1 day; Plain Serum: 1 day |
| Refrigerated | LipoTube Serum: 8 days; Plain Serum: 8 days |
| Frozen | All tubes: 15 days |