Lymphocyte Activity Profile
Use
The Lymphocyte Activity Profile is a test designed to measure the activity and distribution of various subsets of lymphocytes using flow cytometry. It provides diagnostic and prognostic insights into immune function by analyzing markers on lymphocytes, making it particularly relevant in the context of immune disorders, infections, and monitoring the immune response.
Special Instructions
Not provided.
Limitations
This test has not been cleared or approved by the FDA, which may have implications for its use in certain clinical scenarios. The stability of specimens is limited to room temperature, and they are not stable if refrigerated or frozen. Hemolysis, contamination, or clotting can be causes for rejection of the specimen. Additionally, testing schedules may vary, and additional time should be allowed for confirmatory or reflex testing.
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 65759-3 - T-cell subsets CD4+CD8 pnl Bld
- 770-8 - Neutrophils NFr Bld Auto
- 736-9 - Lymphocytes NFr Bld Auto
- 5905-5 - Monocytes NFr Bld Auto
- 713-8 - Eosinophil NFr Bld Auto
- 706-2 - Basophils NFr Bld Auto
- 75652-8 - Imm Lymphs Bld Ql
- 751-8 - Neutrophils # Bld Auto
- 731-0 - Lymphocytes # Bld Auto
- 742-7 - Monocytes # Bld Auto
- 711-2 - Eosinophil # Bld Auto
- 704-7 - Basophils # Bld Auto
- 71695-1 - Imm Granulocytes NFr Bld Auto
- 53115-2 - Imm Granulocytes # Bld Auto
- 58413-6 - nRBC Bld Auto-Rto
- 18314-5 - Morphology Bld-Imp
- 8122-4 - CD3 Cells # Bld
- 8124-0 - CD3 Cells NFr Bld
- 24467-3 - CD3+CD4+ Cells # Bld
- 8123-2 - CD3+CD4+ Cells NFr Bld
- 14135-8 - CD3+CD8+ Cells # Bld
- 8101-8 - CD3+CD8+ Cells NFr Bld
- 13333-0 - CD3+CD25+ Cells NFr Bld
- 26997-7 - CD3+CD25+ Cells # Bld
- 13338-9 - CD8+CD57+ Cells NFr Bld
- 18350-9 - CD8+CD57+ Cells # Bld
- 54218-3 - CD3+CD4+ Cells/CD3+CD8+ Cll Bld
- 6690-2 - WBC # Bld Auto
- 789-8 - RBC # Bld Auto
- 718-7 - Hgb Bld-mCnc
- 4544-3 - Hct VFr Bld Auto
- 787-2 - MCV RBC Auto
- 785-6 - MCH RBC Qn Auto
- 786-4 - MCHC RBC Auto-EntMCnc
- 788-0 - Erythrocyte DistWidth Bld Auto
- 777-3 - Platelet # Bld Auto
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
Fill tube(s) to capacity.
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tube and yellow-top (ACD-A) or (ACD-B) tube
Collection Instructions
Invert tube 8 to 10 times immediately after collection. To preserve cellular viability, draw specimen so it will arrive in the laboratory within 48 hours of collection. Indicate date and time of venipuncture on the tube(s) and on the test request form.
Storage Instructions
Maintain specimen at room temperature. Do not freeze or refrigerate.
Causes for Rejection
Specimen refrigerated or frozen; clotted specimen; hemolysis; contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Yellow-top (ACD-A) or (ACD-B) tube: 2 days, Lavender-top (EDTA) tube: 1 day |
| Refrigerated | Unstable |
| Frozen | Unstable |
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