MaterniT21 PLUS Core (chr21,18,13) NO Gender
Use
The MaterniT21 PLUS test is a comprehensive NIPT for the analysis of chromosomal regions including trisomies 21, 18, and 13, for pregnancies at increased risk of fetal abnormalitites.
Special Instructions
Not provided.
Limitations
This test does not replace the accuracy of prenatal diagnosis methods such as chorionic villus sampling (CVS) or amniocentesis. Discordant results may occur due to a variety of factors, including placental, maternal, or fetal mosaicism, and prior maternal organ transplant. It is not intended to identify pregnancies at risk for neural tube defects or ventral wall defects. The testing may not accurately identify fetal triploidy or the precise locations of subchromosomal duplications or deletions. Factors such as maternal BMI, weight, and systemic lupus erythematosus (SLE) can impact the results.
Methodology
NGS (Targeted)
Biomarkers
LOINC Codes
- 53693-8 - GA Est from conception date
- 75605-6 - cfDNA.fet/cfDNA.total SFr Fetus
- 75980-3 - Fet 13+18+21+X+Y aneup Plas.cfDNA
- 72486-4 - Lab director name Provider
- 75983-7 - Fet Chr 21 Ts Plas.cfDNA Ql
- 75558-7 - Fet Ts 18 risk WBC.DNA+cfDNA Ql
- 73824-5 - Fet Ts 13 risk Plas.cfDNA Ql
- 75693-2 - Fet sex Plas.cfDNA Dosage cfDNA
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
8 mL
Container
Black-and-tan-top (Streck) tube (whole blood). Sequenom collection kits are available.
Collection Instructions
Only the Sequenom collection kit PS#116373 can be used for collection.
Storage Instructions
Room temperature. Do not refrigerate or freeze. Keep out of direct sunlight. Samples must be shipped to LabCorp in a Sequenom collection kit.
Causes for Rejection
Gestational age less than nine weeks; expired or incorrect blood tubes; quantity not sufficient for analysis; received more than seven days from collection; excessive hemolysis; frozen specimens
Other tests from different labs that may be relevant