Multiple Myeloma (MM) Profile, FISH
Also known as: Monoclonal Gammopathy of Undetermined Significance (MGUS), Plasma Cell Leukemia
Use
Diagnostic test for multiple myeloma. Plasma cell enrichment diagnosis increased as much as 50% to 100%. The FISH results on the enriched assay should not be used as a quantitative assay, since the abnormal cells do not represent the percentage of abnormal cells in the aspirate.
Special Instructions
Not provided.
Limitations
This test will not detect molecular mutations or chromosomal alterations not targeted by the included probes. The FISH results on the enriched assay should not be used as a quantitative assay, as the abnormal cells do not represent the percentage of abnormal cells in the aspirate. Comparison to previous results on un-enriched specimens is not recommended.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 31208-2 - Specimen source
- 62361-1 - Cells counted
- 62360-3 - Cells analyzed
- 62357-9 - Chrom analy overall interp-Imp
- 62365-2 - Diagnostic imp Spec-Imp
- 48672-0 - Clinical cytogeneticist Spec
- 11502-2 - Laboratory report
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
1 to 3 mL bone marrow
Minimum Volume
1 mL bone marrow
Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube (suboptimal)
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Whole blood; broken Vacutainer®; specimen received at testing facility 72 hours after collection
Other tests from different labs that may be relevant