Porphyrins, Quantitative, Random Urine
Also known as: Coproporphyrin, Uroporphyrin
Use
Urine porphyrins are useful for the evaluation of cutaneous photosensitivity to exclude porphyria cutanea tarda (PCT). Evaluation of neurologic and/or psychiatric symptoms associated with acute porphyrias, such as acute intermittent porphyria (AIP), requires urine porphobilinogen (PBG) testing. Refer to Porphobilinogen (PBG), Quantitative, Random Urine [003065].
Special Instructions
Refrigerate the specimen and protect it from light during transport. Aliquot into an amber plastic transport tube (LabCorp No. 23598) with an amber cap. If unavailable, cover the tube with aluminum foil and secure it with tape. Clearly label the tube with the patient's name.
Limitations
Results may be affected by the loss of specimen integrity due to exposure to light or lack of refrigeration. Acidic pH or the presence of acid preservatives can compromise the sample quality. The test does not substitute for urine porphobilinogen (PBG) testing when evaluating symptoms associated with acute porphyrias.
Methodology
Chromatography (High-pressure liquid chromatography (HPLC) with fluorometric detection)
Biomarkers
LOINC Codes
- 11228-4
- 2407-5
- 27400-1
- 11221-9
- 9343-5
- 9345-0
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
2 mL
Minimum Volume
1.5 mL
Container
12-mL amber plastic transport tube without preservative
Collection Instructions
Transfer required aliquot into a LabCorp amber plastic transport tube with amber cap (LabCorp No. 23598). If unavailable, cover tube completely with aluminum foil and secure with tape. Label with patient's name.
Storage Instructions
Refrigerate and protect from light.
Causes for Rejection
Stored specimen not refrigerated; specimen exposed to light; acid preservative; pH <3
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unstable |
| Refrigerated | 7 days |
| Frozen | 14 days |