PrEP Use Only: HCV Antibody With Reflex to Quantitative Real-time PCR

Also known as: HCV antibody with reflex, HIV PrEP, pre-exposure prophylaxis screening for HCV

Clinical Use

Use

This test is used for HCV screening and diagnosis in patients administered HIV PrEP and diagnosis of active hepatitis C virus (HCV) infection.

Special Instructions

Not provided.

Limitations

Tests included within this profile may exhibit interference when the sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). Biotin consumption can affect the accuracy of the results, hence patients are advised to stop biotin supplements 72 hours prior to specimen collection. Reflex testing requires additional time and may incur additional charges.

Test Details

Methodology

Immunoassay (Other)

Biomarkers

Hepatitis C virus total antibody

Analyte

Other

Other • Binary (Detected / Not Detected)

Quantitative HCV RNA

Analyte

HCV Quantitation

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

40726-2 - HCV IgG SerPl Ql IA

Result Codes

13955-0 - HCV Ab SerPl Ql IA
11011-4 - HCV RNA SerPl NAA+probe-aCnc
38180-6 - HCV RNA SerPl NAA+probe-Log IU
62365-2 - Diagnostic imp Spec-Imp
19147-8 - Ref Lab Test Ref Range

Result Turnaround Time

1-3 days

Specimen

Serum

Volume

3.0 mL

Minimum Volume

1.5 mL

Container

Gel-barrier tube or serum transfer tube

Collection Instructions

Centrifuge sample within 24 hours of collection. If tube other than a gel-barrier tube is used, or if sample will be shipped frozen, transfer separated serum to a screw-cap polypropylene transport tube. Do not freeze gel-barrier tube (pour off serum first).