PrEP Use Only: HCV Antibody With Reflex to Quantitative Real-time PCR
Also known as: HCV antibody with reflex, HIV PrEP, pre-exposure prophylaxis screening for HCV
Use
This test is used for HCV screening and diagnosis in patients administered HIV PrEP and diagnosis of active hepatitis C virus (HCV) infection.
Special Instructions
PrEP use only. Contains CPT code modifier for CARES Act. If reflex test is performed, additional charges/CPT code(s) may apply. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample due to potential interference.
Limitations
Tests included within this profile may exhibit interference when the sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). Biotin consumption can affect the accuracy of the results, hence patients are advised to stop biotin supplements 72 hours prior to specimen collection. Reflex testing requires additional time and may incur additional charges.
Methodology
Immunoassay (Other)
Biomarkers
LOINC Codes
- 40726-2
- 13955-0
- 11011-4
- 38180-6
- 62365-2
- 19147-8
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.0 mL
Minimum Volume
1.5 mL
Container
Gel-barrier tube or serum transfer tube
Collection Instructions
Centrifuge sample within 24 hours of collection. If tube other than a gel-barrier tube is used, or if sample will be shipped frozen, transfer separated serum to a screw-cap polypropylene transport tube. Do not freeze gel-barrier tube (pour off serum first).
Patient Preparation
Patients should stop biotin consumption at least 72 hours before sample collection.
Storage Instructions
Refrigerated (preferred)
Causes for Rejection
Incorrect anticoagulant; PPT not centrifuged; frozen gel-barrier tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 6 days |
| Frozen | 14 days |