SNP Microarray (Direct)−Prenatal (Reveal®)
Also known as: Prenatal Reveal®
Use
This test detects chromosomal imbalance that could be associated with developmental delay/congenital anomalies. It provides detection of possible uniparental disomy of any chromosome, the percentage and location of homozygosity, including the degree of identity by descent.
Special Instructions
Not provided.
Limitations
This SNP assay does not detect balanced rearrangements, low-level mosaicism (<10%), marker chromosomes that only contain heterochromatin or tetraploidy. This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Microarray
Biomarkers
LOINC Codes
- 31208-2 - Specimen source
- 48000-4 - Chromosome Bld/T
- 62365-2 - Diagnostic imp Spec-Imp
- 48672-0 - Clinical cytogeneticist Spec
Result Turnaround Time
10-21 days
Related Documents
For more information, please review the documents below
Specimen
Amniotic Fluid
Volume
15-20 mL (20-30 mL for early amniocentesis)
Minimum Volume
12 mL
Container
Sterile plastic conical tube
Collection Instructions
Discard first 2 mL of fluid aspirated to avoid maternal cell contamination. Specimen is collected in a 20 mL sterile syringe and transferred aseptically to sterile tubes to be transported to Labcorp. Request form is completed and accompanies specimen and miscellaneous slip to the laboratory.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Rubber stopper and/or frozen specimen cannot be processed.
Other tests from different labs that may be relevant