T-Cell Activation Profile, CD8 Subsets

Casandra

Casandra Test Code LC82574Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 505750CPT Codes 86356, 86359, 86360

T-Cell Activation Profile, CD8 Subsets

Clinical Use

Use

Expanded profile for AIDS monitoring and prognosis. An increase in activation markers is associated with poor prognosis.

Special Instructions

Not provided.

Limitations

The test has been developed and its performance characteristics determined by Labcorp. However, it has not been cleared or approved by the Food and Drug Administration. This could imply limitations in regulatory endorsement and possibly restrictions in clinical use depending on jurisdictional guidelines.

Test Details

Methodology

Cell-based / Cytometry (Flow Cytometry)

Biomarkers

7 targets

CD3+CD3+CD25+CD3+CD4+CD3+CD8+CD4:CD8CD8+CD38+CD8+HLA-DR+

LOINC Codes

Order Codes

65758-5 - T-cell CD4 subset pnl Bld

Result Codes

8122-4 - CD3 Cells # Bld
8124-0 - CD3 Cells NFr Bld
24467-3 - CD3+CD4+ Cells # Bld
8123-2 - CD3+CD4+ Cells NFr Bld
14135-8 - CD3+CD8+ Cells # Bld
8101-8 - CD3+CD8+ Cells NFr Bld
54218-3 - CD3+CD4+ Cells/CD3+CD8+ Cll Bld
16107-5 - CD8+HLA-DR+ Cells # Bld
13337-1 - CD8+HLA-DR+ Cells NFr Bld
13333-0 - CD3+CD25+ Cells NFr Bld
26997-7 - CD3+CD25+ Cells # Bld
13344-7 - CD8+CD38+ Cells NFr Bld
21374-4 - CD8+CD38+ Cells # Bld
6690-2 - WBC # Bld Auto
789-8 - RBC # Bld Auto
718-7 - Hgb Bld-mCnc
4544-3 - Hct VFr Bld Auto
787-2 - MCV RBC Auto
785-6 - MCH RBC Qn Auto
786-4 - MCHC RBC Auto-EntMCnc
788-0 - Erythrocyte DistWidth Bld Auto
777-3 - Platelet # Bld Auto
770-8 - Neutrophils NFr Bld Auto
736-9 - Lymphocytes NFr Bld Auto
5905-5 - Monocytes NFr Bld Auto
713-8 - Eosinophil NFr Bld Auto
706-2 - Basophils NFr Bld Auto
75652-8 - Imm Lymphs Bld Ql
751-8 - Neutrophils # Bld Auto
731-0 - Lymphocytes # Bld Auto
742-7 - Monocytes # Bld Auto
711-2 - Eosinophil # Bld Auto
704-7 - Basophils # Bld Auto
71695-1 - Imm Granulocytes NFr Bld Auto
53115-2 - Imm Granulocytes # Bld Auto
58413-6 - nRBC Bld Auto-Rto
18314-5 - Morphology Bld-Imp

Result Turnaround Time

1-3 days

Specimen

Whole Blood

Volume

Fill tube(s) to capacity.

Minimum Volume

Not provided

Container

Lavender-top (EDTA) tube and yellow-top (ACD-A) or (ACD-B) tube

Collection Instructions

Invert tube 8 to 10 times immediately after collection. To preserve cellular viability, collect specimen so it will arrive in the laboratory within 48 hours of collection.