Alternative Complement Pathway Functional, Serum
Also known as: AH50
Use
This assay evaluates the functional integrity of the alternative complement pathway, useful for screening suspected deficiencies in alternative pathway components (such as C3, factor B, factor D, properdin, factor H, factor I), and in contexts including atypical hemolytic uremic syndrome, C3 glomerulopathy, dense‑deposit disease, and other complement-mediated disorders.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (ELISA)
Biomarkers
Alternative Complement Path Functional assay
Other
Result Turnaround Time
6-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
red-top tube (no gel)
Collection Instructions
Immediately after specimen collection, place the tube on wet ice; centrifuge at 4 °C and aliquot serum into plastic vial; freeze specimen within 30 minutes.
Patient Preparation
Fasting preferred
Storage Instructions
Transport frozen
Other tests from different labs that may be relevant