Beta-Amyloid 42/40 Ratio and Apolipoprotein E (APOE) Isoform Panel, CSF
Also known as: ABeta 42, ABeta 40, AB40, AB42, Alzheimer's Disease (AD)
Use
This panel of LC/MS/MS assays measures Beta‑Amyloid 42/40 Ratio and ApoE Isoform and Total ApoE in cerebrospinal fluid (CSF). The results are analyzed via an algorithm to calculate a risk assessment score, categorizing patients into low, intermediate, or high risk of having Alzheimer’s disease (AD). ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/Chantilly/test/423826?utm_source=openai))
Special Instructions
Collect and transport CSF in a polypropylene tube; store frozen. Note that Quest Diagnostics does not perform this test for individuals under the age of 18. Pre‑test and post‑test counseling is strongly recommended. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/Chantilly/test/423826?utm_source=openai))
Limitations
Not provided.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
6-13 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
1.6 mL
Minimum Volume
0.8 mL
Container
Polypropylene tube
Collection Instructions
Collect and transport CSF in a polypropylene tube
Storage Instructions
Store frozen
Causes for Rejection
Hemolysis, lipemic, collected in glass, polystyrene, or polycarbonate tube, icteric
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 5 days |
| Frozen | 31 days |