Casandra
Casandra Test Code QD35180Version 1 (DRAFT)
Performing Lab
Factor XI Mutation Analysis (Ashkenazi Jewish)
Also known as: Factor XI Deficiency, Plasma Thromboplastin Antecedent (PTA) Deficiency, Rosenthal Syndrome
Clinical Use
Order TestUse
This test identifies Ashkenazi‑Jewish individuals who are at risk of having prolonged bleeding incidents (especially during surgery) due to mutations in the Factor XI (F11) gene.
Special Instructions
Not provided.
Limitations
These mutations account for more than 99% of disease‑causing mutations in the Ashkenazi Jewish population.
Test Details
Methodology
PCR-based (PCR)
Biomarkers
F11
GeneSNV/Indel
Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
9 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
3 mL
Container
EDTA (lavender‑top) tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 days |
| Refrigerated | 8 days |
| Frozen | Unacceptable |
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