Use

HDL Cholesterol Subclasses testing provides a detailed breakdown of HDL particle sizes—specifically measuring HDL‑2 (large HDL) and HDL‑3 (small HDL) subclasses. Large HDL particles are considered most efficient in reverse cholesterol transport and cholesterol clearance by the liver, and low levels of large HDL are correlated with increased cardiovascular disease risk. This subclass analysis offers insights beyond conventional lipid panels by assessing residual cardiovascular risk related to HDL particle functionality and subtype distribution.