Casandra
Casandra Test Code QD63721Version 1 (DRAFT)
Performing Lab
LGI1 Antibody Test
Clinical Use
Order TestUse
Leucine‑rich glioma‑inactivated 1 (LGI1) antibody testing is used in the evaluation of autoimmune encephalitis, particularly VGKC‑complex limbic encephalitis. It is often considered when patients present with cognitive impairment, seizures, faciobrachial dystonic seizures, psychiatric symptoms, and refractory hyponatremia, as early detection can guide immunotherapy and improve outcomes.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
New York Approved
Methodology
Immunoassay (Immunofluorescence Assay)
Biomarkers
LGI1 Antibody
ProteinIFA
Other • Binary (Detected / Not Detected)
LOINC Codes
Order Codes
- 50398-7 - Narrative diagnostic report-Imp
Result Codes
- 19146-0 - Ref Lab Test Results
- 8251-1 - Service Cmnt-Imp
- 49549-9 - Ref lab test method
- 8265-1 - Service Cmnt 04-Imp
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
Not provided
Minimum Volume
0.5 mL
Container
screw capped plastic vial
Collection Instructions
Centrifuge, separate serum from cells and send.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 28 days |
| Frozen | 28 days |
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