Phospholipase A2 Receptor (PLA2R) Antibody Panel
Also known as: Primary Membranous Nephropathy, Membranous Nephropathy, Glomerulonephritis, Anti-PLA2R, Idiopathic Membranous Nephropathy
Use
Phospholipase A2 Receptor (PLA2R) Antibody (Ab) testing provides physicians with a non‑invasive tool for diagnosing primary membranous nephritis (PMN), an autoimmune disease most commonly mediated by autoantibodies to the podocyte antigen, PLA2R. PLA2R Ab is a highly specific biomarker for PMN and is detected in about 70‑80% of patients. Moreover, PLA2R Ab levels frequently rise and fall with the clinical course of PMN and PLA2R Ab levels may have clinical utility in monitoring PMN patients for therapeutic response, remission, and disease relapse.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (Other)
Biomarkers
PLA2R antibody
Protein
Result Turnaround Time
4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 21 days |
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