Synaptophysin, IHC with Interpretation
Use
Synaptophysin is a calcium-binding glycoprotein present in presynaptic vesicles of neurons and neuroendocrine cells. It serves as a broad-spectrum neuroendocrine marker and aids in diagnosing tumors with neuroendocrine differentiation. Interpretation by a qualified pathologist in clinical context is essential.
Special Instructions
Interpretive report is provided. A pathology report is typically required. Slides or blocks must be handled according to IHC specimen requirements (e.g., FFPE tissue).
Limitations
Interpretation should be performed in conjunction with morphological evaluation and clinical history. Inadequate tissue or poor slide quality may compromise results.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Formalin-fixed, paraffin embedded tissue block or FFPE slides
Collection Instructions
Submit a formalin-fixed, paraffin-embedded tissue block or unstained FFPE slide mounted on charged slide.
Storage Instructions
Room temperature
Causes for Rejection
Unlabeled/mislabeled block; insufficient tissue; broken or poor-quality slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinite |
| Frozen | Unacceptable |