2,3 Dinor-11Beta-Prostaglandin F2 Alpha, 24-Hour Urine
Also known as: BETA PG U
Use
This test is used to screen for mast cell activation disorders. Elevated levels of 2,3-dinor-11beta-prostaglandin F2 alpha in urine can indicate conditions such as systemic mast cell disease, angioedema, diffuse urticaria, and some myeloproliferative diseases without diffuse mast cell proliferation.
Special Instructions
Not provided.
Limitations
Elevated levels of 2,3BPG in urine are not specific to systemic mast cell disorders as they may also appear in other conditions such as angioedema and myeloproliferative diseases without corresponding mast cell proliferation. Additionally, the accuracy of this test can be affected by the prior consumption of aspirin or NSAIDs, which are known to reduce prostaglandin levels.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
2,3 Dinor-11Beta-Prostaglandin F2 Alpha
Analyte
LOINC Codes
- 94381-1 - 2,3-dinor 11B-PG F2a/Creat 24h Ur
- 2162-6 - Creat 24h Ur-mRate
- 20624-3 - Creat 24h Ur-mCnc
- 13362-9 - Specimen collect Time Ur
- 3167-4 - Specimen vol 24h Ur
Result Turnaround Time
9-15 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
2.7 mL
Container
ARUP standard transport tubes
Collection Instructions
Collect 24-hour urine collection with a total volume greater than 300 mL. Refrigerate during collection.
Patient Preparation
Discontinue aspirin 2 weeks or NSAIDs 72 hours prior to specimen collection.
Storage Instructions
Refrigerated transport is primary; frozen is also acceptable.
Causes for Rejection
Total collection volume less than 300 mL.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
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