Acetylcholine Receptor Ganglionic (Alpha 3) Antibody
Also known as: a3-AChR Antibody, nAChR Ganglionic Neuronal Antibody
Use
The G‑nAChR autoantibody assay identifies autoantibodies to the ganglionic (alpha‑3) nicotinic acetylcholine receptor. It aids in diagnosing autoimmune autonomic ganglionopathy (AAG), differentiating immunotherapy‑responsive AAG from idiopathic autonomic neuropathy. Elevated antibody levels may suggest a paraneoplastic cause—particularly small‑cell lung cancer or thymoma—where detection can lead to focused tumor evaluation and immunologic treatment and improved outcomes. ([jdos.nicholsinstitute.com](https://jdos.nicholsinstitute.com/dos/BPMC/test/538647?utm_source=openai))
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (RIA)
Biomarkers
Result Turnaround Time
7-14 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
transport tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 48 hours |
| Frozen | 75 days |
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