Ganglionic Acetylcholine Receptor Antibody
Also known as: GANG ACHR
Use
The Ganglionic Acetylcholine Receptor Antibody test is utilized for the detection of antibodies against the ganglionic acetylcholine receptor. This test is significant in the diagnosis of autoimmune autonomic neuropathies, including Autoimmune Autonomic Ganglionopathy (AAG). It aids clinicians in confirming the presence of these antibodies, which are often associated with certain neurological disorders. Identification of these antibodies can assist in the diagnosis and differentiation of autoimmune neurological conditions, directing appropriate medical management and treatment plans.
Special Instructions
Ensure specimen is collected in a Plain Red or Serum Separator Tube (SST). The specimen should be separated from cells as soon as possible or within 2 hours of collection, and transferred to an ARUP Standard Transport Tube. After separation, store the specimen refrigerated if not immediately processed or sent for testing. Avoid exposure to multiple freeze/thaw cycles as it may impact test results.
Limitations
The test is a laboratory-developed test (LDT) with performance characteristics determined by ARUP Laboratories, and it has not been FDA cleared or approved. While the test is CLIA certified, results should be interpreted in conjunction with clinical findings and other laboratory results. Direct assay correlations and cross-reactivities vary between tests and these limitations should be kept in mind when interpreting results. Additionally, specimen quality such as lipemia, icterus, or hemolysis may affect the accuracy of the test results. Plasma specimens are unacceptable for this test.
New York Approved
Methodology
Immunoassay (RIA)
Biomarkers
LOINC Codes
- 42233-7
Result Turnaround Time
2-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated.
Causes for Rejection
Plasma. Grossly lipemic, icteric, or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month (avoid multiple freeze/thaw cycles) |
Other tests from different labs that may be relevant