Casandra
Casandra Test Code QD52191Version 1 (DRAFT)
Performing Lab
Alpha‑1‑Antitrypsin (AAT) Quantitation and Phenotype
Clinical Use
Order TestUse
This test provides both quantitative measurement of alpha‑1‑antitrypsin (AAT) protein concentration in serum and phenotypic determination of AAT variants via isoelectric focusing electrophoresis. It is used to evaluate for AAT deficiency, which can predispose patients to early-onset emphysema and liver dysfunction, and supports identification of common phenotypes such as S and Z alleles and less common variants.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Immunoassay (Immunoturbidimetric Assay)
Biomarkers
2 components
Quantitation • Immunoturbidimetric AssayPhenotype • Immunoturbidimetric Assay
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
2 mL
Minimum Volume
0.6 mL
Container
Transport tube
Storage Instructions
Refrigerated (cold packs)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 7 days |
| Frozen | 30 days |
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