Cold Agglutinin Titer, Quantitative
Use
Detection of the presence of cold agglutinins in patients with suspected cold agglutinin disease
Special Instructions
This test is not specific for Mycoplasma pneumoniae. For diagnosis of Mycoplasma pneumoniae infections, see Mycoplasma pneumoniae, DNA PCR [138420]. Transport blood immediately to laboratory. Incubate at 37°C and allow to clot at 37°C. If there is not a 37°C incubator, allow to clot at room temperature and separate serum from cells immediately after clotting.
Limitations
False-negative results may occur if the sample is refrigerated prior to the separation of the serum from the red blood cells. This test is not a direct measure of the clinical significance of the cold agglutinin and must be used in conjunction with the patient’s clinical presentation and other laboratory values. Individuals may have low levels of cold agglutinins that have no clinical significance.
Methodology
Other
Biomarkers
LOINC Codes
- 5098-9
- 5098-9
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Transport blood immediately to laboratory. Incubate at 37°C and allow to clot at 37°C. Separate serum from cells. If there is not a 37°C incubator, allow to clot at room temperature and separate serum from cells immediately after clotting.
Storage Instructions
Do not refrigerate prior to separation of serum from red cells. Store separated serum in refrigerator.
Causes for Rejection
Refrigeration of the specimen before separating serum from cells
Other tests from different labs that may be relevant