FISH, ALL, Pre‑B Panel
Also known as: ALL (B-Cell), FISH
Use
Fluorescence in situ Hybridization (FISH) panel designed for evaluating acute lymphoblastic leukemia (ALL), particularly Pre‑B subtype. It detects genetic abnormalities such as rearrangements, gains, or losses in key loci including 11q (MLL), chromosomes 4, 10, 17, t(9;22), and t(12;21), which carry diagnostic, prognostic, and therapeutic implications in leukemia management.
Special Instructions
Not provided.
Limitations
The performance characteristics were validated under CLIA regulations and intended for clinical use. The test is not FDA-cleared or approved. Interpretation should consider that undetected abnormalities may exist outside the targeted loci or at levels below assay sensitivity.
Methodology
Chromosomal / Cytogenetics
Biomarkers
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
3 mL
Minimum Volume
1 mL
Container
green‑top (sodium heparin) vacutainer tube
Collection Instructions
Submit 1 to 3 mL of bone marrow in a green-top (sodium heparin) vacutainer tube
Other tests from different labs that may be relevant