Acute Lymphoblastic Leukemia (ALL) Panel by FISH, Adult
Also known as: FISH A ALL
Use
The Acute Lymphoblastic Leukemia (ALL) Panel by FISH is designed for adults with newly diagnosed ALL. It is used to detect recurrent genetic abnormalities through rearrangements, providing information helpful in the diagnosis, prognosis, and treatment decisions for patients with ALL. FISH testing can identify specific chromosomal changes associated with ALL, potentially guiding therapeutic choices and risk stratification.
Special Instructions
A processing fee will apply if the procedure is canceled after setup or if sample integrity is inadequate. Other specimen types may be acceptable; contact the Cytogenetics Laboratory for specific instructions. This test must be ordered using Oncology test request form #43099 or through the ARUP interface. If multiple FISH tests are ordered, processing fees will only be applied once. Ensure that the ordering includes the clinical indication and specimen type.
Limitations
Paraffin-embedded specimens and clotted specimens are unacceptable. Stability is limited to 48 hours at ambient or refrigerated temperatures; samples frozen are unacceptable. While FISH can detect certain chromosomal rearrangements, some potential partners for these rearrangements may not be identified, which limits the interpretability of rearrangement results.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 57802-1
- 11526-1
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
3 mL
Minimum Volume
1 mL
Container
Green (sodium heparin) tube
Collection Instructions
Ensure the sample is collected in a heparinized syringe; other specimen types may require different handling.
Storage Instructions
Store and transport at room temperature.
Causes for Rejection
Paraffin-embedded specimens, clotted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant