Human Immunodeficiency Virus Type 1 (HIV-1) GenoSure Archive
Also known as: HIV GSARCH
Use
The HIV-1 GenoSure Archive test is designed for patients with an undetectable viral load. It provides genotypic information about resistance to antiretroviral drugs, specifically targeting protease inhibitors, reverse transcriptase inhibitors, and integrase inhibitors. The test analyzes cell-associated viral DNA, offering insights into drug susceptibility based on detected mutations. This information assists healthcare providers in tailoring antiretroviral therapy for individuals with HIV-1, enhancing clinical decision-making for managing resistance and optimizing treatment regimens.
Special Instructions
Not provided.
Limitations
The test is performed by Monogram Biosciences and not by ARUP, which means turnaround and reporting might vary. It is crucial that specimens are not thawed as it will lead to rejection. The test has not been cleared or approved by the FDA, so results should not be the sole criteria for patient management. The determined HIV-1 subtype and the analysis are based on specific coding regions, and any external factors affecting DNA can impact results.
New York Approved
Methodology
NGS (Targeted)
Biomarkers
Integrase
ProteinProtease
ProteinReverse Transcriptase
Protein
LOINC Codes
- 80695-0 - HIV 1 proviral DNA Gentyp Bld MC Doc
- 93047-9 - Specimen condition
- 80693-5 - HIV1 provir DNA RT + PR + IN Mut Det Seq
- 80694-3 - HIV1 proviral DNA Gentyp Bld MC Nar
Result Turnaround Time
22-28 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
1 mL
Container
Lavender (EDTA) tube
Collection Instructions
Freeze immediately. Transport in the original collection tube.
Storage Instructions
CRITICAL FROZEN.
Causes for Rejection
Thawed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | Unacceptable |
| Frozen | 2 weeks |
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