ImmuKnow®

Casandra

Casandra Test Code LC83851Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 176120CPT Code 86352

Also known as: Cellular Function Assay (involving stimulation and detection of a biomarker), Cylex Immune Assay, Immuno Test, Immunosuppression Level Assay

Clinical Use

Order Test

Use

This test is a transplant physician's means of obtaining and monitoring information about immune status. ImmuKnow® measures the adenosine triphosphate (ATP) response of stimulated peripheral blood lymphocytes.

Special Instructions

Prior to initial submission of specimens for this test, contact HLA customer service (800-533-1037) to establish special specimen collection and transportation arrangements. These specimen collection and transportation arrangements must be observed in order to obtain acceptable results.

Limitations

The assay must be set up within 30 hours of specimen collection; specimens received after 30 hours are not acceptable for testing. Specimens cannot be chilled, refrigerated, or frozen and must be maintained at room temperature. Further, results of the ImmuKnow® test should be used in conjunction with clinical presentation, medical history, and other clinical indicators to accurately establish the immune status of a patient.

Test Details

Methodology

Other

Biomarkers

ATP in peripheral blood lymphocytes

Analyte

ATP Level • Concentration / Level • Categorical (e.g., Positive / Negative / Indeterminate)

LOINC Codes

Order Codes

53939-5

Result Codes

53939-5

Result Turnaround Time

2-4 days

Specimen

Whole Blood

Volume

6 to 8 mL

Minimum Volume

2 to 4 mL

Container

Green-top (sodium heparin) tube only

Collection Instructions

Do not use lithium heparin, ACD, or EDTA tubes. Assay must be set up within 30 hours of specimen collection. Specimens received after 30 hours are not acceptable for testing.

Storage Instructions

Maintain specimen at room temperature (ie, 18°C to 28°C) only. Specimen stable 30 hours; >30 hours specimen not viable. Do not refrigerate or freeze specimen.