Immunofixation (IFE) and Protein Electrophoresis, 24-Hour Urine

Casandra

Casandra Test Code LC75161Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 003467CPT Codes 84156, 84166, 86335

Immunofixation (IFE) and Protein Electrophoresis, 24-Hour Urine

Also known as: Bence Jones Protein Identification, 24-Hour Urine, Globulins, 24-Hour Urine, IFE/Protein Electrophoresis, 24-Hour Urine, Myeloma Proteins, 24-Hour Urine

Clinical Use

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Use

Useful in characterizing the species of protein or proteins in cases of proteinuria. Techniques can identify albumin, γ globulin, γ globulin fragments (light chains, Bence Jones proteins). Of value in the study of monoclonal gammopathies, lymphoproliferative diseases, including lymphoma; special application to multiple myeloma, macroglobulinemia of Waldenström and amyloidosis. Monoclonal gammopathy (M spike) work-up.

Special Instructions

The request form must include the patient's age and clinical diagnosis. When submitting a specimen for this test, be sure to label it appropriately and complete all necessary documentation for accurate processing.

Limitations

While the test is proficient at identifying and characterizing proteins in urine, limitations may arise from improper sample collection or storage, potentially affecting the accuracy of results. False negatives could occur in cases where protein concentration is below the test's sensitivity threshold. Additionally, external factors such as specimen handling or exposure to preservatives may lead to test rejection.

Test Details