Immunoglobulins, CSF Quantitative

Casandra

Casandra Test Code AR52406Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0050631CPT Code 82784

Immunoglobulins, CSF Quantitative

Also known as: QNTIG CSF

Clinical Use

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Use

This test aids in the diagnosis of immune-mediated disorders affecting the nervous system. High or abnormal levels of immunoglobulins in the cerebrospinal fluid can indicate diseases such as multiple sclerosis, other demyelinating conditions, or infections that affect the central nervous system. By quantitatively measuring immunoglobulins A, G, and M in the CSF, clinicians can differentiate these diseases from other conditions or identify the underlying cause of neurological symptoms.

Special Instructions

Centrifuge and separate to remove cellular material and transfer 1 mL CSF to an ARUP Standard Transport Tube. The minimum volume required for testing is 0.6 mL. The specimen must be refrigerated during transport. Grossly bloody or hemolyzed specimens are unacceptable and may adversely affect results.

Limitations

The test's results might be falsely elevated due to hemolysis or the presence of red blood cells in the CSF specimen. Such conditions can impact the reliability of IgG, IgA, and IgM measurements, making it crucial to interpret results with caution especially when the specimen is hemolyzed. Furthermore, the presence of systemic contamination or inappropriate handling can further skew results, necessitating strict adherence to collection and handling instructions.

Test Details

FDA Approved