p63 by Immunohistochemistry

Casandra

Casandra Test Code AR36207Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2004073CPT Code 88342

p63 by Immunohistochemistry

Also known as: P63 IHC

Clinical Use

Order Test

Use

The p63 by Immunohistochemistry test is used as part of diagnostic procedures in pathology to identify and study specific cellular proteins within tissues or cells. p63, a member of the p53 family, is pivotal in identifying certain types of epithelial cells, thereby aiding in the differentiation of tumors, assessing the origin of malignant cells, and supporting histopathological evaluations. It often plays a significant role in the diagnosis of cancers and helps differentiate squamous cell carcinoma from other neoplasms.

Special Instructions

Not provided.

Limitations

This test is provided solely as a technical service. Interpretive services are not included, and the test results should be correlated with clinical and other diagnostic findings for comprehensive diagnosis. It may not detect small focal areas or all protein expressions, depending on the tissue or cellular context, fixation quality, and other pre-analytical variables. Limitations inherent in immunohistochemistry, such as cross-reactivity, false positives, and variations in staining intensity, may occur.

Test Details

New York Approved

Methodology

Immunoassay (IHC)

Biomarkers

p63

Protein

IHC

Expression • Categorical (e.g., Positive / Negative / Indeterminate)

LOINC Codes

Result Codes

94736-6 - Tissue block ID Spec

Result Turnaround Time

1-3 days

Specimen

Tissue (FFPE)

Volume

Not provided

Minimum Volume

2 slides

Container

Tissue transport kit (ARUP supply #47808)

Collection Instructions

Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides.