PML/RARA FISH Panel
Use
Fluorescence in situ hybridization (FISH), acute myelocytic leukemia (AML), and PML/RARA
Special Instructions
Include pertinent clinical diagnosis and previous cytogenetic studies on the test request form. Utilize sterile technique and Labcorp transport kits when possible.
Limitations
Molecular mutations or chromosomal alterations not targeted by the probe included in this profile will not be detected. This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. Additionally, any FISH study should avoid using EDTA tubes if sharing with a karyotype study due to growth inhibition in cell culture.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 31208-2
- 48672-0
- 48674-6
- 62360-3
- 62361-1
- 77031-3
- 62361-1
- 62360-3
- 48674-6
- 77031-3
- 31208-2
- 48672-0
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube (suboptimal).
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Transport to the testing laboratory at room temperature; use of a cool pack or a Labcorp transport kit is acceptable. Do not allow samples to overheat or freeze.
Causes for Rejection
Broken Vacutainer®; broken or stained slides; decalcified bone core; frozen specimen; quantity not sufficient for analysis.
Other tests from different labs that may be relevant