Porphobilinogen, Quantitative, Random Urine (6329)
Also known as: PBG
Use
Measurement of porphobilinogen in random urine specimens is used for biochemical diagnosis of acute porphyrias including acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria, particularly during symptomatic episodes.
Special Instructions
Specimens must be protected from light; no preservative required; optimal pH 6–7; storage and stability requirements must be followed to preserve analyte integrity.
Limitations
Porphobilinogen may degrade rapidly if specimen is exposed to light or improper pH; not FDA‐cleared but validated under CLIA. Assay performance may be affected by transport time and specimen handling.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
2 mL Random Urine
Minimum Volume
1 mL Random Urine
Container
Sterile Container
Collection Instructions
No preservatives. Protect specimen from light. Optimal pH is 6‑7.
Storage Instructions
Refrigerate‑OK/Frozen‑OK; room temp unacceptable
Causes for Rejection
Not protected from light
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 7 Days |
| Frozen | 30 Days |
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