RB1 Oncology Fluorescence in situ Hybridization (FISH)
Also known as: Leukemia FISH, Lymphoma FISH
Use
Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)
Special Instructions
For samples where karyotype (510999) and any FISH study are in the same tube, use of EDTA is not recommended due to potential growth inhibition in cell culture. Utilize sterile technique and Labcorp transport kits when possible for specimen collection.
Limitations
This test does not detect molecular mutations or chromosomal alterations not targeted by the probe included in this profile. As the performance characteristics were determined by Labcorp, it has not been cleared or approved by the FDA.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 31208-2
- 48674-6
- 50398-7
- 48672-0
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube (suboptimal)
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen
Other tests from different labs that may be relevant