Serum Integrated 2

Casandra

Casandra Test Code LC17268Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 017270CPT Codes 81511, 82105, 82677, 84702, 86336

Also known as: AFP, Maternal Serum, Down Syndrome

Clinical Use

Order Test

Use

Screening test for open neural tube defects, Down syndrome, and trisomy 18

Special Instructions

Not provided.

Limitations

This is a screening test requiring two specimens collected in different trimesters. A positive screening result indicates that diagnostic testing may be advised to determine the presence of a neural tube defect or chromosomal abnormality. The test's performance characteristics have not been cleared or approved by the FDA, implying potential limitations in regulatory acceptance for clinical diagnostics.

Test Details

Methodology

Immunoassay (CLIA)

Biomarkers

5 targets

AFPDIAhCGPAPP-AuE3

LOINC Codes

Result Codes

49586-1 - Integrated scn Patient-Imp
18185-9 - GA
29463-7 - Weight
48407-1 - PAPP-A SerPl-mCnc
76348-2 - PAPP-A adj MoM SerPl
1834-1 - AFP SerPl-mCnc
23811-3 - AFP adj MoM SerPl
19080-1 - HCG SerPl-aCnc
32166-1 - HCG adj MoM SerPl
2250-9 - u Estriol SerPl-mCnc
21264-7 - u Estriol adj MoM SerPl
23883-2 - Inhibin A SerPl-mCnc
36904-1 - Inhibin A adj MoM SerPl
48803-1 - Neural tube defect risk Fetus
43995-0 - Ts 21 risk Fetus
49090-4 - Fet Ts 21 risk from Mat age
43994-3 - Ts 18 risk Fetus
47223-3 - Fet Ts 18 risk from Mat age

Result Turnaround Time

2-5 days

Specimen

Serum

Volume

5 mL

Minimum Volume

3 mL

Container

Gel-barrier tube

Collection Instructions

Collect in serum separator tube with gel barrier. Allow blood to clot, avoiding hemolysis. Separate serum from cells by centrifugation. Transport spun tube to testing laboratory.