Casandra
Casandra Test Code QD10301Version 1 (DRAFT)
Performing Lab
Sickle Cell Screen
Also known as: Hemoglobin S
Clinical Use
Order TestUse
This is a screening test to determine the presence of sickling hemoglobins (e.g., hemoglobin S, hemoglobin C‑Harlem), used to assess individuals at risk of sickle cell crises in conditions like prolonged anoxia during surgery, athletic programs, or high altitude environments.
Special Instructions
Not provided.
Limitations
Not appropriate for patients less than 6 months old due to interference by fetal hemoglobin (Hemoglobin F).
Test Details
Methodology
Other
Biomarkers
Hemoglobin C‑Harlem
ProteinPresence • Other • Binary (Detected / Not Detected)
Hemoglobin S
ProteinPresence • Other • Binary (Detected / Not Detected)
Result Turnaround Time
0 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
0.5 mL
Container
EDTA (lavender‑top) tube
Collection Instructions
Maintain specimen at room temperature. Do not centrifuge.
Causes for Rejection
Gross hemolysis • Grossly lipemic • Clotted
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
Related Tests
Other tests from different labs that may be relevant
Hemoglobin S, Sickle Solubility
ARUP Laboratories
Hemoglobin (Hb) Solubility
Labcorp
Hemoglobin (Hb) Solubility With Reflex to Hemoglobinopathy Fractionation Cascade, Blood
Labcorp
Sickle Solubility, Blood
Mayo Clinic Lab
Hemoglobin S Evaluation with Reflex to RBC Solubility
ARUP Laboratories
Sickle Cell, Fetal Analysis
Labcorp
Hemoglobin Evaluation by HPLC With Reflex to Electrophoresis and/or RBC Solubility
ARUP Laboratories
Hemoglobin Evaluation Reflexive Cascade
ARUP Laboratories
High-Performance Liquid Chromatography (HPLC) Hemoglobin Variant, Blood
Mayo Clinic Lab
Beta-Thalassemia and Hemoglobinopathy via the HBB Gene
Prevention Genetics
