ACTH by Immunohistochemistry
Also known as: ACTH IHC
Use
Immunohistochemical detection of ACTH (adrenocorticotropic hormone) in tissue or cell‑block specimens, useful for identifying ACTH expression in tumors—typically pituitary adenomas or ectopic hormone–producing lesions—to assist in pathologic classification.
Special Instructions
Submit electronic request; if electronic ordering not available, use ARUP Immunohistochemistry Stain Form (#32978) with client number. Use ARUP Immunohistochemistry Stain Offerings brochure for offerings. This test is performed as a stain‑and‑return (technical) service only.
Limitations
Performed only as a technical immunohistochemistry stain without pathologist interpretation. Only tissue or cell block specimens accepted; non‑representative or depleted specimens are unacceptable. Slides must not be oven baked. Frozen specimens unacceptable.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
5 unstained (3- to 5‑micron thick) slides or tissue block
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) & paraffin embed; cells must be prepared into cellblock; protect block/slides from excessive heat; if sending precut slides, do not oven bake.
Storage Instructions
Room temperature or refrigerated; ship in cooled container during summer months.
Causes for Rejection
Non‑representative tissue type; depleted specimens; frozen specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |