Allergen, Mites, Lepidoglyphus destructor
Also known as: LEPIDOGLY
Use
This test measures allergen-specific IgE levels to Lepidoglyphus destructor, providing insight into potential allergic reactions. The quantitative ImmunoCAP fluorescent enzyme immunoassay delivers results in kilounits per liter (kU/L), aiding in the diagnosis and management of allergic diseases where dust mite sensitivity is suspected. The results must be interpreted in conjunction with clinical history and other diagnostic tests, such as skin testing, to understand their significance and potential implications for patient care. A direct correlation between IgE concentrations and clinical severity or in vivo reactivity should not be assumed.
Special Instructions
Multiple patient encounters should be avoided during the preparation for this test. Ensure the use of a serum separator tube and follow specific specimen handling and transport instructions to maintain sample integrity. The stability of the specimen varies with the storage condition—ambient, refrigerated, or frozen. Refer to the laboratory’s detailed specimen collection instructions for multiple allergen orders.
Limitations
The test may not entirely predict clinical reactivity, and a negative result does not exclude the possibility of an allergy or anaphylactic response. The presence of allergen-specific IgE indicates sensitization but does not necessarily correlate with the severity of clinical symptoms. Results categorized in the 0.10-0.34 kU/L range are especially challenging as their clinical relevance remains undetermined without specialist interpretation. Variations in IgE concentrations do not uniformly correlate with specific clinical reactions or skin test outcomes, emphasizing the need for integration with clinical history.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescent Enzyme Immunoassay)
Biomarkers
LOINC Codes
- 6160-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.25 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect using a serum separator tube. Separate serum from cells ASAP or within 2 hours of collection.
Patient Preparation
Multiple patient encounters should be avoided.
Storage Instructions
Refrigerated storage is recommended for transport.
Causes for Rejection
Hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |