Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor (AMPAR) Antibody, IgG by CBA-IFA With Reflex to Titer, Serum
Also known as: AMPA SER
Use
Aid in diagnosis of limbic encephalitis. May be used in monitoring treatment response in individuals who are antibody positive. The presence of AMPA receptor antibodies may be associated with psychosis, with or without seizures; AMPA encephalitis may be paraneoplastic but tumor type is variable (thymic, lung, and breast cancer).
Special Instructions
If Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antibody, IgG by IFA with Reflex to Titer, Serum is positive, then an Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antibody Titer, IgG, Serum is reported. Additional charges apply.
Limitations
A negative test result does not rule out a diagnosis of autoimmune encephalitis. Results should be interpreted in correlation with the patient's clinical history and other laboratory findings.
New York Approved
Methodology
Immunoassay (Cell-based Indirect Fluorescent Antibody)
Biomarkers
LOINC Codes
- 82733-7
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.15 mL
Container
ARUP standard transport tube
Collection Instructions
Serum separator tube (SST) or plain red.
Storage Instructions
Refrigerated.
Causes for Rejection
Hemolyzed, contaminated, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |