Autoimmune Myelopathy Panel, Serum
Also known as: AIMYS
Use
The Autoimmune Myelopathy Panel, Serum is used to evaluate rapid-onset neurologic symptoms associated with spinal cord dysfunction. Testing is performed on both serum and cerebrospinal fluid (CSF) to maximize diagnostic yield for autoimmune myelopathies. This panel includes tests that detect antibodies associated with autoimmune neurologic diseases, which may present with symptoms such as optic neuritis, transverse myelitis, and other spinal cord dysfunctions.
Special Instructions
Not provided.
Limitations
A negative result does not rule out a diagnosis of autoimmune neurologic disease. Results should be interpreted in the context of the patient's clinical history and other laboratory findings. While antibodies are indicative, they are not exclusively diagnostic for any single condition and must be considered as part of a broader clinical picture.
New York Approved
Methodology
Cell-based / Cytometry (Indirect Fluorescent Antibody, Immunoblot)
Biomarkers
LOINC Codes
- 94385-2 - Amphiphysin IgG Ser Ql Line blot
- 56540-8 - GAD65 Ab Ser IA-aCnc
- 61177-2 - Paraneoplastic Ab Ser Ql IF
- 63439-4 - AQP4 H2O channel IgG SerPl Ql IF
- 72504-4 - CV2 Ab SerPl Ql IF
- 93428-1 - GABABR IgG SerPl Ql CBA IFA
- 91545-4 - MOG Ab Ser Ql CBA IFA
- 82444-1 - Glial nuc type 1 Ab Ser Ql Line blot
- 94676-4 - DPPX IgG Ser Ql CBA IFA
- 93498-4 - mGluR1 IgG Ser Ql CBA IFA
Result Turnaround Time
3-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1.5 mL
Container
Serum separator tube (SST)
Collection Instructions
Separate from cells ASAP or within 2 hours of collection. Transfer three 1 mL serum aliquots to ARUP standard transport tubes.
Storage Instructions
Frozen
Causes for Rejection
Amniotic fluid, ocular fluid, peritoneal fluid, synovial fluid, CSF, or plasma. Contaminated, hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 1 month |
Other tests from different labs that may be relevant