C-MYC by Immunohistochemistry
Also known as: CMYCIHC
Use
The C-MYC by Immunohistochemistry test is utilized to qualitatively detect the expression of the c-Myc protein in tissue or cell samples. c-Myc is a regulator gene and proto-oncogene that plays a vital role in cell cycle progression, apoptosis, and cellular transformation, and its overexpression is associated with various human cancers. The test aids in the diagnostic evaluation and characterization of neoplastic conditions where c-Myc protein might be implicated.
Special Instructions
This test is performed as a stain and return (technical) service only. Submit electronic request or use the ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number if electronic ordering is unavailable.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration, but it has been developed and its performance characteristics determined by ARUP Laboratories under a CLIA certified laboratory setting. The test is intended for clinical purposes, and results should be interpreted in the context of a total immune profile, clinical history, and relevant morphological and cytogenetic data.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 42794-8
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
tissue block or 5 unstained positively charged slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport in a tissue transport kit (ARUP supply #47808).
Storage Instructions
Room temperature, also acceptable: Refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |