C-MYC by Immunohistochemistry

Casandra

Casandra Test Code AR15164Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2008317CPT Code 88342

C-MYC by Immunohistochemistry

Also known as: CMYCIHC

Clinical Use

Order Test

Use

The C-MYC by Immunohistochemistry test is utilized to qualitatively detect the expression of the c-Myc protein in tissue or cell samples. c-Myc is a regulator gene and proto-oncogene that plays a vital role in cell cycle progression, apoptosis, and cellular transformation, and its overexpression is associated with various human cancers. The test aids in the diagnostic evaluation and characterization of neoplastic conditions where c-Myc protein might be implicated.

Special Instructions

Not provided.

Limitations

This test has not been cleared or approved by the US Food and Drug Administration, but it has been developed and its performance characteristics determined by ARUP Laboratories under a CLIA certified laboratory setting. The test is intended for clinical purposes, and results should be interpreted in the context of a total immune profile, clinical history, and relevant morphological and cytogenetic data.

Test Details

New York Approved

Methodology

Immunoassay (IHC)

Biomarkers

c-Myc

Protein

IHC

Expression • Ordinal Score (e.g., TPS, CPS, H-score)

LOINC Codes

Result Codes

42794-8 - MYC gene Mut Anl Bld/T
94736-6 - Tissue block ID Spec

Result Turnaround Time

1-3 days

Specimen

Tissue (FFPE)

Volume

Not provided

Minimum Volume

Not provided

Container

tissue block or 5 unstained positively charged slides

Collection Instructions

Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport in a tissue transport kit (ARUP supply #47808).