Calcitonin by Immunohistochemistry
Also known as: CALCIT IHC
Use
An immunohistochemical stain for calcitonin, performed as a technical “stain and return” service, primarily used to assess tissue samples—particularly thyroid C‑cells and medullary thyroid carcinoma—by identifying calcitonin expression in fixed, embedded specimens.
Special Instructions
Submit electronic request or use ARUP Immunohistochemistry Stain Form (#32978) if electronic ordering is unavailable. Use tissue transport kit (ARUP supply #47808) for transport. Protect specimens from excessive heat; if using precut slides, do not oven bake.
Limitations
Specimens must be representative tissue; depleted specimens are unacceptable. Frozen specimens are unacceptable. Non‑representative tissue types and depleted specimens lead to rejection. Slides must not be oven‑baked.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
5 unstained (3‑ to 5‑micron thick) slides (Min: 2 slides) or tissue block
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen; cell blocks for cells. Transport tissue block or unstained slides in tissue transport kit (ARUP supply #47808). If sending precut slides, do not oven bake.
Storage Instructions
Room temperature or refrigerated; ship in cooled container during summer months.
Causes for Rejection
Non‑representative tissue type; depleted specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |