Epstein-Barr Virus Antibody Panel I
Also known as: EBV PAN
Use
This test aids in the diagnosis of primary Epstein-Barr virus infectious mononucleosis after a suspected false-negative heterophile antibody (Monospot) test. It evaluates the presence of various EBV-specific antibodies, providing vital information for clinicians regarding the status of an EBV infection, which can assist in diagnosing and managing the patient's condition.
Special Instructions
When processing this test, ensure to collect the specimen in a serum separator tube (SST), allowing it to clot completely at room temperature before separating from cells. Label specimens appropriately as 'acute' or 'convalescent'. Parallel testing is preferred and convalescent specimens should be received within 30 days from receipt of acute specimens.
Limitations
The test has its limitations in conditions where the specimens are contaminated, heat-inactivated, icteric, or grossly hemolyzed. These conditions lead to rejection. Additionally, improper storage conditions such as repeated freeze/thaw cycles can affect the integrity of the specimen, potentially impacting test results. The results need careful correlation with clinical findings as repeat testing may be necessary where indeterminate results are found.
New York Approved
Methodology
Immunoassay (Chemiluminescent Immunoassay)
Biomarkers
LOINC Codes
- 50969-5
- 7885-7
- 7886-5
- 30083-0
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
Serum separator tube (SST)
Collection Instructions
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transport to an ARUP standard transport tube. Label specimens plainly as 'acute' or 'convalescent.'
Storage Instructions
Refrigerated
Causes for Rejection
Contaminated, heat-inactivated, icteric, or grossly hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (Avoid repeated freeze/thaw cycles) |