Glucose Transporter-1 (GLUT-1) by Immunohistochemistry
Also known as: GLUT1 IHC
Use
The GLUT-1 test by immunohistochemistry is used to evaluate the expression of Glucose Transporter-1 protein in tissue samples. This test can aid in the diagnosis of certain cancers and other diseases where GLUT-1 overexpression is implicated. The interpretation of staining patterns and intensity helps pathologists to determine the potential involvement of GLUT-1 in a specific pathological condition, contributing to the overall clinical assessment.
Special Instructions
The test is submitted as a stain and return (technical) service only, which requires an electronic request or the use of an ARUP Immunohistochemistry Stain Form if electronic ordering is unavailable. The tissue block or slides must be transported using an ARUP tissue transport kit, and precautions should be taken to protect specimens from excessive heat.
Limitations
The GLUT-1 IHC test is performed in a CLIA-certified laboratory as a Laboratory Developed Test, but it has not been cleared or approved by the FDA. Results should be interpreted in the context of other clinical and laboratory findings and may not be definitive on their own. The test is subject to variations based on specimen handling, and degraded or improperly preserved samples may lead to inaccurate results.
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Collect tissue or cells and fix in 10 percent neutral buffered formalin. Paraffin embed the specimen. Transport in a tissue transport kit. Do not oven bake precut slides.
Storage Instructions
Ship at room temperature or refrigerated. Use a cooled container during summer months.
Causes for Rejection
Non-representative tissue type or depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
