HNF-1B by Immunohistochemistry
Also known as: HNF1B IHC
Use
This is an immunohistochemical stain for hepatocyte nuclear factor‑1 beta (HNF‑1B), performed as a stain‑and‑return (technical) service to allow pathological assessment of HNF‑1B expression in formalin‑fixed, paraffin‑embedded tissue. It is intended for clinical purposes and supports diagnostic interpretation by clinicians and pathologists.
Special Instructions
This test is performed as a stain and return (technical) service only. It is a laboratory‑developed test (LDT), performed in a CLIA‑certified laboratory. Refer to the ARUP Immunohistochemistry Stain Offerings brochure for ordering recommendations.
Limitations
This test was developed and its performance characteristics were determined by ARUP Laboratories and has not been cleared or approved by the US Food and Drug Administration. It provides only the technical IHC stain; interpretation must be performed separately by a pathologist.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (3‑ to 5‑micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808). Min: 2 slides. If sending precut slides, do not oven bake.
Storage Instructions
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non‑representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |