Microsporidia Stain by Modified Trichrome
Also known as: MICROST
Use
The Microsporidia Stain by Modified Trichrome test is used for the detection of microsporidia in stool specimens, particularly to confirm suspicions of infection when PCR results are negative but clinical suspicion remains high. Microsporidia are obligate intracellular parasites that can cause diarrheal diseases, primarily in immunocompromised individuals. Accurate detection is essential for appropriate treatment planning and monitoring of infections.
Special Instructions
For optimal results, it is recommended to collect three separate stool specimens within a 5-7-day period with individual orders submitted for each specimen. Ensure specimens are preserved within one hour of collection using either AlcorFix or 10 percent formalin. ARUP provides AlcorFix through eSupply accessible via ARUP Connect.
Limitations
A single negative result does not rule out the possibility of a Microsporidia infection as there are limitations in sensitivity. Therefore, repeated testing or alternative methods like PCR might be necessary for comprehensive evaluation.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 32701-5
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
Not provided
Minimum Volume
1 g
Collection Instructions
Preserve 2 g of stool within one hour of collection in AlcorFix or 10 percent formalin. Additional instructions are available online.
Causes for Rejection
Unpreserved stool or specimens in any other preservative than indicated.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 9 months |
| Refrigerated | 9 months |
| Frozen | Unacceptable |